21 cities
| City | County | 2026 Pop. ↓ |
|---|---|---|
| Hilton Head Island | Beaufort County | 38,444 |
| Hanahan | Berkeley County | 22,684 |
| Hardeeville | Jasper County | 16,926 |
| Hartsville | Darlington County | 7,321 |
| Homeland Park | Anderson County | 7,094 |
| Hollywood | Charleston County | 5,607 |
| Honea Path | Anderson County | 3,981 |
| Hilltop | Spartanburg County | 3,764 |
| Hampton | Hampton County | 2,552 |
| Hopkins | Richland County | 1,750 |
| Homewood | Horry County | 1,711 |
| Holly Hill | Orangeburg County | 1,242 |
| Hamer | Dillon County | 905 |
| Heath Springs | Lancaster County | 905 |
| Harleyville | Dorchester County | 774 |
| Helena | Newberry County | 703 |
| Hickory Grove | York County | 476 |
| Hemingway | Williamsburg County | 449 |
| Hilda | Barnwell County | 422 |
| Harbor Island | Beaufort County | 382 |
| Hodges | Greenwood County | 166 |