| City | 2026 Pop. ↓ |
|---|---|
| Shiraz | 1,798,531 |
| Sanandaj | 502,807 |
| Shahriar | 476,853 |
| Sari | 338,471 |
| Shahr-e Kord | 270,560 |
| Sabzevar | 269,930 |
| Semnan | 268,651 |
| Saveh | 267,686 |
| Shahin Shahr | 253,555 |
| Sirjan | 231,151 |
| Saqqez | 231,131 |
| Shahrud | 171,475 |
| Shahreza | 160,446 |
| Shahr-e Sadra | 151,456 |
| Sahand | 136,010 |
| Shush | 127,196 |
| Salmas | 102,778 |
| Shushtar | 92,678 |
| Sarpol-e Dhahab | 73,367 |
| Shirvan | 72,590 |
| Sabashahr | 70,797 |
| Shahr-e Jadid-e Hashtgerd | 69,489 |
| Susangerd | 68,795 |
| Shahr-e Babak | 67,158 |
| Salehieh | 63,629 |
| Sowmeeh Sara | 62,157 |
| Saravan | 60,454 |
| Sheybani | 59,971 |
| Sardasht | 56,227 |
| Shahin Dezh | 54,424 |
| Sarakhs | 54,336 |
| Safadasht | 53,544 |
| Sarab | 45,403 |
| Sonqor | 42,892 |
| Shahedshahr | 38,284 |
| Showt | 36,910 |
| Sardrud | 36,466 |
| Sahneh | 33,527 |
| Semirom | 30,987 |
| Safashahr | 28,699 |
| Shadegan | 26,086 |