Santa Isabel's 2026 population is now estimated at 5,136. In 2000, the population of Santa Isabel was 6,993. Santa Isabel experienced a decrease of -49 residents over the past year, marking an annual decline of -0.95%. These population values and projections come from U.S. Census decennial place populations for Puerto Rico (2000, 2010, 2020) and World Population Review Internal Projections .
| City | 2026 Pop. ↓ | Growth |
|---|---|---|
| San Juan | 291,890 | -1.67% |
| Bayamón | 154,106 | -1.17% |
| Carolina | 127,767 | -1.31% |
| Ponce | 95,462 | -2.03% |
| Guaynabo | 64,631 | -0.96% |
| Caguas | 64,010 | -1.55% |
| Mayagüez | 50,991 | -2% |
| Trujillo Alto | 41,101 | -1.02% |
| Arecibo | 37,129 | -1.08% |
| Fajardo | 23,098 | -1.4% |
| Vega Baja | 22,037 | -1.01% |
| Cataño | 20,599 | -1.93% |
| Guayama | 16,789 | -1.86% |
| Canóvanas | 16,121 | 5.08% |
| Candelaria | 13,532 | -1.33% |
| Humacao | 13,132 | -2.16% |
| Cayey | 12,602 | -1.74% |
| Yauco | 11,775 | -2.34% |
| Dorado | 11,564 | -0.85% |
| Hormigueros | 10,323 | -1.16% |
| Aguadilla | 9,696 | -1.96% |
| Manatí | 9,478 | -2.41% |
| Río Grande | 9,329 | -1.9% |
| San Lorenzo | 9,063 | 0.74% |
| Sabana Grande | 8,758 | 0.44% |
| Isabela | 8,736 | -1.58% |
| Juncos | 8,614 | 0.82% |
| Corozal | 8,606 | -1.03% |
| San Germán | 8,245 | -1.79% |
| Coamo | 8,191 | -2.1% |
| Pájaros | 8,052 | -1.42% |
| Vega Alta | 8,039 | -1.52% |
| San Sebastián | 7,846 | -1.27% |
| Sabana Seca | 7,487 | -1.6% |
| Cabo Rojo | 7,412 | -1.72% |
| Aibonito | 7,382 | -0.7% |
| San Antonio (Dorado Municipio) | 7,219 | -0.3% |
| San Isidro | 7,066 | 0.21% |
| Juana Díaz | 7,033 | -0.73% |
| Utuado | 6,576 | -1.51% |
| Arroyo | 6,468 | 0.06% |
| Quebradillas | 5,896 | 0.68% |
| Gurabo | 5,851 | -1.63% |
| Luquillo | 5,755 | -1.86% |
| Lares | 5,182 | 0.33% |
| Santa Isabel | 5,136 | -0.95% |
| Puerto Real | 5,052 | -1.06% |
| Las Piedras | 4,789 | -1.28% |
| Yabucoa | 4,744 | -1.52% |
| Lajas | 4,403 | -0.27% |
| Peñuelas | 4,389 | -1.79% |
| Sabana Hoyos | 4,372 | 5.12% |
| Ceiba | 4,212 | -1.8% |
| Cidra | 4,197 | -1.22% |
| Breñas | 4,185 | 1.36% |
| Coco | 4,114 | -2.09% |
| Adjuntas | 4,033 | -0.54% |
| Comunas | 3,983 | 4.73% |
| Tierras Nuevas Poniente | 3,934 | 1.24% |
| Florida | 3,906 | -1.16% |
| Toa Alta | 3,803 | 0.16% |
| Añasco | 3,688 | -1.97% |
| Barceloneta | 3,645 | -0.25% |
| Salinas | 3,586 | -1.75% |
| Guánica | 3,551 | -4.39% |
| Aguilita | 3,518 | -1.84% |
| Naguabo | 3,492 | -1.5% |
| Imbéry | 3,487 | -0.68% |
| Candelaria Arenas | 3,484 | -2% |
| Hatillo | 3,440 | -1.57% |
| Bajadero | 3,414 | -0.52% |
| Celada | 3,414 | -1.1% |
| Naranjito | 3,386 | 4.57% |
| Patillas | 3,289 | -1.7% |
| Jayuya | 3,263 | 1.05% |
| Campanilla | 3,178 | -4.71% |
| Villalba | 3,118 | -0.51% |
| Ciales | 2,980 | 0.88% |
| Camuy | 2,901 | -1.49% |
| Punta Santiago | 2,869 | -3.37% |
| Santo Domingo | 2,844 | -0.63% |
| Guayanilla | 2,790 | -2.14% |
| Capitanejo | 2,783 | -2.18% |
| Santa Bárbara | 2,772 | -3.14% |
| Monte Grande | 2,760 | -0.11% |
| Loíza | 2,750 | -2.1% |
| Aguada | 2,636 | -1.24% |
| La Dolores | 2,632 | -0.98% |
| San Antonio (Quebradillas Municipio) | 2,618 | 2.71% |
| Ceiba | 2,597 | -1.63% |
| Comerío | 2,590 | -2.7% |
| Luis Lloréns Torres | 2,574 | -0.77% |
| Aguas Buenas | 2,560 | -3.03% |
| La Alianza | 2,480 | 1.51% |
| Cabán | 2,420 | -1.98% |
| La Luisa | 2,331 | -0.68% |
| Emajagua | 2,262 | -1.44% |
| Carrizales | 2,243 | -1.23% |
| Luyando | 2,232 | -1.59% |
| Monserrate | 2,187 | -1.09% |
| Coto Laurel | 2,181 | -2.07% |
| Espino | 2,177 | 3.42% |
| Potala Pastillo | 2,138 | -2.29% |
| Galateo | 2,032 | -1.5% |
| Vieques | 2,021 | -3.02% |
| Ingenio | 2,015 | -4.86% |
| Palomas (Comerío Municipio) | 2,006 | 1.21% |
| Campo Rico | 1,988 | -2.55% |
| Barahona | 1,974 | -1.4% |
| Boquerón (Cabo Rojo Municipio) | 1,929 | -0.31% |
| San José | 1,920 | -2.54% |
| La Fermina | 1,909 | -2.25% |
| Coquí | 1,901 | -3.4% |
| Aguas Claras | 1,876 | -2.9% |
| Bayamón | 1,857 | -0.59% |
| María Antonia | 1,823 | 2.19% |
| Rafael González | 1,813 | -1.47% |
| Jauca | 1,791 | 0.96% |
| Boquerón (Las Piedras Municipio) | 1,732 | 3.22% |
| Barranquitas | 1,724 | -2.71% |
| H. Rivera Colón | 1,705 | -2.24% |
| Martorell | 1,679 | -1.76% |
| Piedra Gorda | 1,659 | -0.96% |
| Los Llanos | 1,653 | -1.55% |
| Las Marías | 1,626 | -1.39% |
| Vázquez | 1,610 | -1.04% |
| Río Cañas Abajo | 1,607 | 2.82% |
| Fránquez | 1,604 | -1.17% |
| Rafael Capó | 1,603 | -0.37% |
| San Antonio (Aguadilla Municipio) | 1,562 | -1.39% |
| Hato Candal | 1,539 | -1.79% |
| Olimpo | 1,526 | -1.86% |
| Vieques | 1,524 | -1.55% |
| Tallaboa Alta | 1,516 | -1.11% |
| Mariano Colón | 1,508 | -2.46% |
| Morovis | 1,507 | -1.89% |
| Rincón | 1,498 | 0.2% |
| Río Lajas | 1,495 | -2.86% |
| Sabana | 1,492 | -0.53% |
| Maunabo | 1,491 | -0.67% |
| Orocovis | 1,445 | 4.48% |
| Jobos | 1,434 | -3.37% |
| G. L. García | 1,430 | -1.31% |
| Luis M. Cintrón | 1,421 | -2.94% |
| Río Blanco | 1,408 | -1.12% |
| Guayabal | 1,403 | -2.3% |
| Mora | 1,380 | -0.86% |
| Culebra | 1,358 | -1.02% |
| Lluveras | 1,355 | -1.53% |
| Playita Cortada | 1,340 | -1.62% |
| Suárez | 1,338 | -2.26% |
| Ramos | 1,331 | -1.92% |
| Miranda | 1,323 | -1.93% |
| Animas | 1,297 | 0.46% |
| Coto Norte | 1,283 | -1.38% |
| Daguao | 1,260 | -1.49% |
| El Mangó | 1,258 | -1.02% |
| Pole Ojea | 1,247 | -1.89% |
| Playa Fortuna | 1,245 | -1.89% |
| Antón Ruíz | 1,242 | -1.51% |
| Corazón | 1,235 | -3.36% |
| Parcelas Nuevas | 1,230 | -1.6% |
| Tiburones | 1,211 | -1.78% |
| Indios | 1,205 | -1.31% |
| Palomas (Yauco Municipio) | 1,174 | -3.06% |
| Playita (Yabucoa Municipio) | 1,169 | -1.76% |
| Corcovado | 1,158 | -1.19% |
| Sabana Eneas | 1,134 | -2.07% |
| Búfalo | 1,133 | 1.16% |
| La Playa | 1,112 | -3.22% |
| Bartolo | 1,093 | -1.09% |
| Mucarabones | 1,089 | -2.16% |
| Central Aguirre | 1,075 | -1.19% |
| Cacao | 1,069 | 0.38% |
| Aceitunas | 1,060 | -1.94% |
| Buena Vista (Arroyo Municipio) | 1,059 | -2.75% |
| Rafael Hernández | 1,047 | -1.6% |
| Toa Baja | 1,047 | -2.24% |
| Las Ollas | 1,029 | -2.56% |
| Stella | 1,023 | -0.39% |
| Pueblito del Río | 1,017 | -1.55% |
| Juncal | 994 | 0% |
| Palmarejo (Lajas Municipio) | 972 | 0% |
| Tallaboa | 965 | 0.21% |
| Palmer | 961 | -0.41% |
| Pastos | 958 | -2.74% |
| Las Marías | 955 | 1.06% |
| Candelero Arriba | 947 | -1.56% |
| El Ojo | 946 | -2.67% |
| Liborio Negrón Torres | 940 | -1.05% |
| Benítez | 933 | -2.51% |
| La Parguera | 933 | -0.64% |
| Rosa Sánchez | 912 | -0.87% |
| Duque | 903 | -2.38% |
| Marueño | 894 | -0.78% |
| Peña Pobre | 834 | -1.07% |
| Garrochales | 831 | -1.66% |
| Santa Clara | 830 | -1.07% |
| Hato Arriba | 822 | 1.23% |
| Magas Arriba | 817 | -2.39% |
| Esperanza | 814 | -2.51% |
| Bajandas | 805 | -3.01% |
| Cayuco | 802 | -2.08% |
| Parcelas La Milagrosa | 788 | -3.08% |
| Jagual | 763 | -2.05% |
| Playita (Salinas Municipio) | 707 | 1.58% |
| Betances | 704 | -1.4% |
| Lomas | 698 | -1.83% |
| Palmarejo (Coamo Municipio) | 686 | -2.83% |
| Maricao | 673 | -1.46% |
| Palo Seco | 672 | -2.47% |
| El Negro | 658 | -3.09% |
| Yaurel | 638 | -3.04% |
| Pajonal | 636 | -0.93% |
| Quebrada | 606 | -3.04% |
| Las Ochenta | 595 | -2.78% |
| Moca | 550 | -5.01% |
| Fuig | 546 | -4.21% |
| Parcelas Peñuelas | 540 | -3.4% |
| Lamboglia | 534 | -4.13% |
| La Plena | 460 | -3.97% |