| City | County | 2026 Pop. ↓ |
|---|---|---|
| Clinton | Hinds County | 26,323 |
| Columbus | Lowndes County | 22,507 |
| Corinth | Alcorn County | 14,291 |
| Clarksdale | Coahoma County | 13,403 |
| Canton | Madison County | 10,857 |
| Cleveland | Bolivar County | 9,911 |
| Columbia | Marion County | 6,476 |
| Carthage | Leake County | 4,859 |
| Crystal Springs | Copiah County | 4,591 |
| Collins | Covington County | 2,212 |
| Cleary | Rankin County | 2,179 |
| Collinsville | Lauderdale County | 1,826 |
| Charleston | Tallahatchie County | 1,645 |
| Calhoun City | Calhoun County | 1,444 |
| Columbus AFB | Lowndes County | 1,367 |
| Coldwater | Tate County | 1,313 |
| Caledonia | Monroe County | 1,110 |
| Centreville | Wilkinson County | 1,059 |
| Conehatta | Newton County | 1,056 |
| Como | Panola County | 1,053 |
| Coffeeville | Yalobusha County | 774 |
| Cloverdale | Adams County | 735 |
| Crenshaw | Panola County | 605 |
| Crowder | Quitman County | 513 |
| Courtland | Panola County | 484 |
| Crawford | Lowndes County | 414 |
| Carrollton | Carroll County | 400 |
| Clara | Wayne County | 341 |
| Chunky | Newton County | 268 |
| Cruger | Holmes County | 238 |
| Cary | Sharkey County | 216 |
| Crosby | Amite County | 211 |
| Coahoma | Coahoma County | 209 |