Cuenca's 2025 population is now estimated at 461,143. In 1950, the population of Cuenca was 39,418. Cuenca has grown by 8,151 in the last year, which represents a 1.8% annual change. These population estimates and projections come from the latest revision of the UN World Urbanization Prospects . These estimates represent the Urban agglomeration of Cuenca, which typically includes Cuenca's population in addition to adjacent suburban areas.