Santiago de Cuba
- Country:
- Cuba
- Continent:
- North America
Santiago de Cuba's 2025 population is now estimated at 443,285. In 1950, the population of Santiago de Cuba was 149,674. Santiago de Cuba has grown by 1,020 in the last year, which represents a 0.23% annual change. These population estimates and projections come from the latest revision of the UN World Urbanization Prospects . These estimates represent the Urban agglomeration of Santiago de Cuba, which typically includes Santiago de Cuba's population in addition to adjacent suburban areas.