City | Rank | County | 2024 Pop. |
|---|---|---|---|
| Pearl | 1 | Rankin County | 28,445 |
| Madison | 2 | Madison County | 28,063 |
| Brandon | 3 | Rankin County | 25,902 |
| Ridgeland | 4 | Madison County | 24,406 |
| Flowood | 5 | Rankin County | 10,820 |
| Canton | 6 | Madison County | 10,684 |
| Kosciusko | 7 | Attala County | 6,763 |
| Forest | 8 | Scott County | 5,231 |
| Carthage | 9 | Leake County | 4,799 |
| Pearl River | 10 | Kemper County | 4,414 |
| Morton | 11 | Scott County | 3,592 |
| Gluckstadt | 12 | Madison County | 3,498 |
| Durant | 13 | Holmes County | 1,953 |
| Lexington | 14 | Holmes County | 1,400 |
| Pelahatchie | 15 | Rankin County | 1,293 |
| Conehatta | 16 | Newton County | 1,223 |
| Goodman | 17 | Holmes County | 1,157 |
| Hillsboro | 18 | Scott County | 934 |
| Pickens | 19 | Holmes County | 811 |
| Standing Pine | 20 | Attala County | 584 |
| Walnut Grove | 21 | Leake County | 505 |
| Redwater | 22 | Attala County | 494 |
| Lake | 23 | Scott County | 465 |
| Harperville | 24 | Scott County | 392 |
| Ethel | 25 | Attala County | 333 |
| Sebastopol | 26 | Scott County | 256 |
| Lena | 27 | Leake County | 152 |
| West | 28 | Holmes County | 131 |
| Sallis | 29 | Attala County | 127 |
| McCool | 30 | Attala County | 105 |