DeSoto County, Madison County, Washington County, Panola County, Tate County, Bolivar County, Leflore County, Yazoo County, Sunflower County, Grenada County, Coahoma County, Holmes County, Yalobusha County, Tallahatchie County, Montgomery County, Carroll County, Tunica County, Humphreys County, Quitman County, Sharkey County, and Issaquena County are the counties generally considered part of Northwest Mississippi.