7 zips
| Zip Code | City | Population ↓ |
|---|---|---|
| 52501 | Ottumwa | 30,341 |
| 52553 | Eddyville | 1,871 |
| 52554 | Eldon | 1,221 |
| 52530 | Agency | 939 |
| 52536 | Blakesburg | 713 |
| 52566 | Kirkville | 254 |
| 52548 | Chillicothe | 50 |
The data shown reflect ZCTAs from the US Census. As of 2024, there are 7 ZCTAs in Wapello County, Iowa (US Census).