| Zip Code | City | Population ↓ |
|---|---|---|
| 35674 | Tuscumbia | 20,214 |
| 35661 | Muscle Shoals | 18,982 |
| 35660 | Sheffield | 9,433 |
| 35646 | Leighton | 4,038 |
| 35616 | Cherokee | 3,599 |
The data shown reflect ZCTAs from the US Census. As of 2024, there are 5 ZCTAs in Colbert County, Alabama (US Census).