| Zip Code | City | Population ↓ |
|---|---|---|
| 72315 | Blytheville | 20,255 |
| 72370 | Osceola | 7,265 |
| 72442 | Manila | 4,447 |
| 72438 | Leachville | 2,469 |
| 72358 | Luxora | 1,648 |
| 72395 | Wilson | 1,229 |
| 72350 | Joiner | 1,018 |
| 72351 | Keiser | 791 |
| 72330 | Dyess | 533 |
| 72426 | Dell | 193 |
| 72428 | Etowah | 117 |
| 72391 | West Ridge | 46 |
| 72313 | Bassett | 0 |
| 72329 | Driver | 0 |
The data shown reflect ZCTAs from the US Census. As of 2024, there are 14 ZCTAs in Mississippi County, Arkansas (US Census).