| Zip Code | City | Population ↓ |
|---|---|---|
| 1002 | Amherst | 22,992 |
| 1027 | Easthampton | 17,711 |
| 1075 | South Hadley | 17,115 |
| 1007 | Belchertown | 15,368 |
| 1060 | Northampton | 14,724 |
| 1003 | Amherst | 11,989 |
| 1082 | Ware | 10,533 |
| 1062 | Florence | 9,491 |
| 1073 | Southampton | 6,185 |
| 1033 | Granby | 6,096 |
| 1035 | Hadley | 5,295 |
| 1050 | Huntington | 2,714 |
| 1096 | Williamsburg | 2,516 |
| 1038 | Hatfield | 2,469 |
| 1063 | Northampton | 2,089 |
| 1053 | Leeds | 1,885 |
| 1039 | Haydenville | 1,728 |
| 1026 | Cummington | 1,073 |
| 1098 | Worthington | 951 |
| 1088 | West Hatfield | 725 |
| 1070 | Plainfield | 571 |
| 1032 | Goshen | 484 |
| 1012 | Chesterfield | 440 |
| 1243 | Middlefield | 135 |
| 1066 | North Hatfield | 134 |
| 1084 | West Chesterfield | 99 |
The data shown reflect ZCTAs from the US Census. As of 2024, there are 26 ZCTAs in Hampshire County, Massachusetts (US Census).