| Zip Code | City | Population ↓ |
|---|---|---|
| 2536 | East Falmouth | 20,909 |
| 2601 | Hyannis | 17,178 |
| 2649 | Mashpee | 15,144 |
| 2532 | Buzzards Bay | 13,092 |
| 2632 | Centerville | 11,929 |
| 2645 | Harwich | 10,930 |
| 2631 | Brewster | 10,176 |
| 2563 | Sandwich | 10,168 |
| 2664 | South Yarmouth | 9,282 |
| 2673 | West Yarmouth | 9,246 |
| 2540 | Falmouth | 8,615 |
| 2648 | Marstons Mills | 7,774 |
| 2675 | Yarmouth Port | 7,185 |
| 2660 | South Dennis | 6,604 |
| 2537 | East Sandwich | 6,408 |
| 2653 | Orleans | 6,322 |
| 2642 | Eastham | 5,724 |
| 2633 | Chatham | 4,667 |
| 2667 | Wellfleet | 3,890 |
| 2644 | Forestdale | 3,838 |
| 2657 | Provincetown | 3,630 |
| 2562 | Sagamore Beach | 3,485 |
| 2655 | Osterville | 3,441 |
| 2639 | Dennis Port | 3,308 |
| 2559 | Pocasset | 3,205 |
| 2638 | Dennis | 3,146 |
| 2635 | Cotuit | 3,007 |
| 2668 | West Barnstable | 2,465 |
| 2556 | North Falmouth | 2,375 |
| 2646 | Harwich Port | 1,950 |
| 2630 | Barnstable | 1,922 |
| 2534 | Cataumet | 1,460 |
| 2670 | West Dennis | 1,340 |
| 2650 | North Chatham | 1,024 |
| 2652 | North Truro | 996 |
| 2659 | South Chatham | 916 |
| 2542 | Buzzards Bay | 766 |
| 2671 | West Harwich | 750 |
| 2666 | Truro | 631 |
| 2561 | Sagamore | 481 |
| 2663 | South Wellfleet | 462 |
| 2637 | Cummaquid | 323 |
| 2641 | East Dennis | 319 |
| 2647 | Hyannis Port | 159 |
| 2553 | Monument Beach | 76 |
| 2672 | West Hyannisport | 28 |
| 2643 | East Orleans | 0 |
The data shown reflect ZCTAs from the US Census. As of 2024, there are 47 ZCTAs in Barnstable County, Massachusetts (US Census).