| Zip Code | City | Population ↓ |
|---|---|---|
| 93446 | Paso Robles | 45,720 |
| 93422 | Atascadero | 33,781 |
| 93420 | Arroyo Grande | 32,126 |
| 93401 | San Luis Obispo | 28,773 |
| 93405 | San Luis Obispo | 24,991 |
| 93444 | Nipomo | 22,079 |
| 93402 | Los Osos | 15,572 |
| 93433 | Grover Beach | 12,755 |
| 93442 | Morro Bay | 11,399 |
| 93465 | Templeton | 9,829 |
| 93449 | Pismo Beach | 8,050 |
| 93445 | Oceano | 6,912 |
| 93410 | San Luis Obispo | 6,523 |
| 93428 | Cambria | 6,056 |
| 93430 | Cayucos | 2,941 |
| 93409 | San Luis Obispo | 2,591 |
| 93453 | Santa Margarita | 2,096 |
| 93432 | Creston | 1,434 |
| 93461 | Shandon | 1,369 |
| 93424 | Avila Beach | 1,174 |
| 93407 | San Luis Obispo | 309 |
| 93452 | San Simeon | 307 |
| 93408 | San Luis Obispo | 11 |
The data shown reflect ZCTAs from the US Census. As of 2024, there are 23 ZCTAs in San Luis Obispo County, California (US Census).