16 ZIP Codes
| Zip Code | City | Population ↓ |
|---|---|---|
| 78521 | Brownsville | 87,380 |
| 78520 | Brownsville | 64,740 |
| 78526 | Brownsville | 60,012 |
| 78550 | Harlingen | 53,335 |
| 78586 | San Benito | 50,964 |
| 78552 | Harlingen | 42,332 |
| 78566 | Los Fresnos | 25,110 |
| 78559 | La Feria | 12,169 |
| 78578 | Port Isabel | 10,016 |
| 78593 | Santa Rosa | 5,455 |
| 78583 | Rio Hondo | 5,236 |
| 78575 | Olmito | 4,575 |
| 78597 | South Padre Island | 2,935 |
| 78592 | Santa Maria | 677 |
| 78535 | Combes | 425 |
| 78567 | Los Indios | 323 |
The data shown reflect ZCTAs from the US Census. As of 2025, there are 16 ZCTAs in Cameron County, Texas (US Census).