| Zip Code | City | Population ↓ |
|---|---|---|
| 99701 | Fairbanks | 18,295 |
| 99760 | Nenana | 761 |
| 99741 | Galena | 627 |
| 99740 | Fort Yukon | 476 |
| 99602 | Holy Cross | 277 |
| 99720 | Allakaket | 256 |
| 99765 | Nulato | 249 |
| 99627 | McGrath | 226 |
| 99777 | Tanana | 214 |
| 99590 | Grayling | 210 |
| 99722 | Arctic Village | 199 |
| 99748 | Kaltag | 197 |
| 99768 | Ruby | 194 |
| 99746 | Huslia | 182 |
| 99758 | Minto | 113 |
| 99781 | Venetie | 109 |
| 99730 | Central | 108 |
| 99788 | Chalkyitsik | 95 |
| 99691 | Nikolai | 91 |
| 99724 | Beaver | 87 |
| 99558 | Anvik | 74 |
| 99754 | Koyukuk | 74 |
| 99665 | Shageluk | 65 |
| 99675 | Takotna | 58 |
| 99733 | Circle | 45 |
| 99767 | Rampart | 41 |
| 99745 | Hughes | 34 |
| 99726 | Bettles Field | 27 |
| 99756 | Manley Hot Springs | 17 |
| 99757 | Lake Minchumina | 14 |
| 99790 | Fairbanks | 13 |
| 99774 | Stevens Village | 9 |
The data shown reflect ZCTAs from the US Census. As of 2024, there are 32 ZCTAs in Yukon-Koyukuk Census Area, Alaska (US Census).