| Zip Code | City | Population ↓ |
|---|---|---|
| 88001 | Las Cruces | 39,358 |
| 88012 | Las Cruces | 31,800 |
| 88011 | Las Cruces | 30,831 |
| 88005 | Las Cruces | 27,279 |
| 88007 | Las Cruces | 24,983 |
| 88021 | Anthony | 16,156 |
| 88008 | Santa Teresa | 11,771 |
| 88063 | Sunland Park | 11,398 |
| 87937 | Hatch | 3,546 |
| 88048 | Mesquite | 3,211 |
| 88072 | Vado | 2,937 |
| 88044 | La Mesa | 2,499 |
| 88002 | White Sands Missile Range | 1,449 |
| 88047 | Mesilla Park | 1,372 |
| 88004 | Las Cruces | 1,037 |
| 87941 | Salem | 860 |
| 88027 | Chamberino | 708 |
| 88046 | Mesilla | 663 |
| 88003 | Las Cruces | 458 |
| 88024 | Berino | 430 |
| 87940 | Rincon | 414 |
| 87936 | Garfield | 234 |
| 88052 | Organ | 98 |
The data shown reflect ZCTAs from the US Census. As of 2024, there are 23 ZCTAs in Doña Ana County, New Mexico (US Census).