| Zip Code | City | Population ↓ |
|---|---|---|
| 13820 | Oneonta | 22,500 |
| 13326 | Cooperstown | 4,698 |
| 13849 | Unadilla | 4,424 |
| 13491 | West Winfield | 3,853 |
| 13439 | Richfield Springs | 3,715 |
| 13825 | Otego | 3,058 |
| 13411 | New Berlin | 2,743 |
| 13843 | South New Berlin | 2,094 |
| 13320 | Cherry Valley | 2,085 |
| 13809 | Mount Upton | 1,964 |
| 12197 | Worcester | 1,951 |
| 12155 | Schenevus | 1,748 |
| 13348 | Hartwick | 1,669 |
| 13315 | Burlington Flats | 1,404 |
| 13808 | Morris | 1,379 |
| 13335 | Edmeston | 1,355 |
| 12116 | Maryland | 1,351 |
| 13807 | Milford | 1,296 |
| 13810 | Mount Vision | 1,260 |
| 13796 | Laurens | 996 |
| 13337 | Fly Creek | 653 |
| 13861 | West Oneonta | 454 |
| 13776 | Gilbertsville | 404 |
| 13468 | Springfield Center | 291 |
| 13342 | Garrattsville | 275 |
| 12064 | East Worcester | 254 |
| 13450 | Roseboom | 252 |
| 13488 | Westford | 141 |
| 13834 | Portlandville | 118 |
| 13859 | Wells Bridge | 101 |
| 13415 | New Lisbon | 82 |
| 13482 | West Burlington | 63 |
| 13333 | East Springfield | 57 |
| 13457 | Schuyler Lake | 32 |
| 13747 | Colliersville | 29 |
The data shown reflect ZCTAs from the US Census. As of 2024, there are 35 ZCTAs in Otsego County, New York (US Census).