| County | Rank | Change (2020) ↓ | 2025 Pop. | 2020 Pop. |
|---|---|---|---|---|
| Franklin County | 1 | 6.2% | 31,294 | 29,468 |
| Piscataquis County | 2 | 5.02% | 17,652 | 16,808 |
| Oxford County | 3 | 5.01% | 60,799 | 57,898 |
| Lincoln County | 4 | 4.79% | 36,951 | 35,263 |
| York County | 5 | 4.52% | 221,858 | 212,260 |
| Waldo County | 6 | 4.27% | 41,350 | 39,658 |
| Androscoggin County | 7 | 3.3% | 114,845 | 111,175 |
| Kennebec County | 8 | 3.2% | 128,707 | 124,712 |
| Cumberland County | 9 | 3.11% | 313,016 | 303,585 |
| Sagadahoc County | 10 | 2.89% | 37,795 | 36,732 |
| Penobscot County | 11 | 2.83% | 156,480 | 152,169 |
| Somerset County | 12 | 2.37% | 51,670 | 50,473 |
| Hancock County | 13 | 1.75% | 56,480 | 55,511 |
| Washington County | 14 | 1.68% | 31,611 | 31,088 |
| Aroostook County | 15 | 0.52% | 67,409 | 67,063 |
| Knox County | 16 | -0.2% | 40,573 | 40,654 |
Maine's counties show varied growth patterns from 2020 to 2025. Franklin County leads with 6.2% annualized growth, followed by Piscataquis County (5.02%) and Oxford County (5.01%). The largest counties are Cumberland County (313,016), York County (221,858), and Penobscot County (156,480). Of the 16 counties in Maine, 15 are growing while just 1 has experienced population decline. Overall, counties averaged 3.2% annualized growth, with total population growing by 3.22% annually.