20 ZIP Codes
| Zip Code | City | Population ↓ |
|---|---|---|
| 16125 | Greenville | 17,178 |
| 16148 | Hermitage | 16,545 |
| 16127 | Grove City | 15,117 |
| 16146 | Sharon | 12,936 |
| 16137 | Mercer | 12,490 |
| 16150 | Sharpsville | 6,856 |
| 16142 | New Wilmington | 5,522 |
| 16159 | West Middlesex | 4,455 |
| 16121 | Farrell | 4,199 |
| 16145 | Sandy Lake | 2,660 |
| 16154 | Transfer | 2,539 |
| 16153 | Stoneboro | 2,234 |
| 16130 | Hadley | 1,810 |
| 16124 | Fredonia | 1,462 |
| 16133 | Jackson Center | 1,425 |
| 16161 | Wheatland | 819 |
| 16114 | Clarks Mills | 579 |
| 16311 | Carlton | 421 |
| 16113 | Clark | 358 |
| 16151 | Sheakleyville | 52 |
The data shown reflect ZCTAs from the US Census. As of 2025, there are 20 ZCTAs in Mercer County, Pennsylvania (US Census).