There are 11 zip codes in Florence County, South Carolina. The most populated is 29501, located in Florence. * 2024 populations estimated based on the latest ACS 5-year data.

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Zip Code
City
Population
29501Florence47,406
29505Florence24,562
29506Florence20,545
29560Lake City12,073
29161Timmonsville10,935
29541Effingham9,836
29555Johnsonville6,043
29583Pamplico5,074
29591Scranton4,565
29530Coward2,597
29114Olanta1,459

Florence County, South Carolina Zip Codes by Population (2024)