17 zips
| Zip Code | City | Population ↓ |
|---|---|---|
| 29115 | Orangeburg | 27,179 |
| 29118 | Orangeburg | 15,676 |
| 29059 | Holly Hill | 5,234 |
| 29048 | Eutawville | 4,680 |
| 29142 | Santee | 4,658 |
| 29047 | Elloree | 3,745 |
| 29112 | North | 3,718 |
| 29018 | Bowman | 3,374 |
| 29039 | Cordova | 3,008 |
| 29107 | Neeses | 2,695 |
| 29038 | Cope | 2,452 |
| 29432 | Branchville | 2,422 |
| 29113 | Norway | 2,186 |
| 29163 | Vance | 1,546 |
| 29146 | Springfield | 1,295 |
| 29133 | Rowesville | 1,198 |
| 29117 | Orangeburg | 422 |
The data shown reflect ZCTAs from the US Census. As of 2024, there are 17 ZCTAs in Orangeburg County, South Carolina (US Census).