31 cities
| City | Rank | County | 2026 Pop. ↓ |
|---|---|---|---|
| Lamar | 1 | Prowers County | 7,610 |
| La Junta | 2 | Otero County | 6,820 |
| Rocky Ford | 3 | Otero County | 3,739 |
| Las Animas | 4 | Bent County | 2,393 |
| Springfield | 5 | Baca County | 1,286 |
| Fowler | 6 | Otero County | 1,176 |
| Ordway | 7 | Crowley County | 1,073 |
| Holly | 8 | Prowers County | 842 |
| Eads | 9 | Kiowa County | 616 |
| Swink | 10 | Otero County | 578 |
| North La Junta | 11 | Bent County | 512 |
| Walsh | 12 | Baca County | 505 |
| Granada | 13 | Prowers County | 447 |
| Wiley | 14 | Prowers County | 435 |
| Manzanola | 15 | Otero County | 319 |
| Olney Springs | 16 | Crowley County | 287 |
| Sugar City | 17 | Crowley County | 241 |
| Cheraw | 18 | Otero County | 227 |
| Crowley | 19 | Crowley County | 155 |
| La Junta Gardens | 20 | Bent County | 115 |
| Pritchett | 21 | Baca County | 105 |
| Vilas | 22 | Baca County | 97 |
| Campo | 23 | Baca County | 94 |
| McClave | 24 | Bent County | 91 |
| Hasty | 25 | Bent County | 82 |
| Haswell | 26 | Kiowa County | 68 |
| Hartman | 27 | Prowers County | 57 |
| Sheridan Lake | 28 | Kiowa County | 54 |
| Two Buttes | 29 | Baca County | 31 |
| Towner | 30 | Kiowa County | 28 |
| Brandon | 31 | Kiowa County | 23 |
Otero County, Prowers County, Bent County, Crowley County, Baca County, and Kiowa County are the counties generally considered part of Southeast Colorado.