23 cities
| City | Rank | County | 2026 Pop. ↓ |
|---|---|---|---|
| Somerset | 1 | Pulaski County | 12,592 |
| Monticello | 2 | Wayne County | 5,711 |
| Columbia | 3 | Adair County | 4,612 |
| Russell Springs | 4 | Russell County | 2,847 |
| Mount Vernon | 5 | Rockcastle County | 2,458 |
| Greensburg | 6 | Green County | 2,277 |
| Liberty | 7 | Casey County | 1,986 |
| Jamestown | 8 | Russell County | 1,898 |
| Albany | 9 | Clinton County | 1,738 |
| Stearns | 10 | McCreary County | 1,530 |
| Burkesville | 11 | Cumberland County | 1,397 |
| Pine Knot | 12 | McCreary County | 1,297 |
| Brodhead | 13 | Rockcastle County | 1,107 |
| Ferguson | 14 | Pulaski County | 868 |
| Burnside | 15 | Pulaski County | 723 |
| Whitley City | 16 | McCreary County | 692 |
| Science Hill | 17 | Pulaski County | 664 |
| Eubank | 18 | Pulaski County | 339 |
| Summersville | 19 | Green County | 312 |
| Pleasant View | 20 | McCreary County | 265 |
| Livingston | 21 | Rockcastle County | 165 |
| McKinney | 22 | Casey County | 41 |
| Marrowbone | 23 | Cumberland County | 19 |
Pulaski County, Wayne County, Adair County, Russell County, Rockcastle County, McCreary County, Casey County, Green County, Clinton County, and Cumberland County are the counties generally considered part of South Kentucky.