5 cities
| City | Rank | County | 2025 Pop. ↓ |
|---|---|---|---|
| Des Arc | 1 | Prairie County | 1,827 |
| Hazen | 2 | Prairie County | 1,366 |
| De Valls Bluff | 3 | Prairie County | 488 |
| Fredonia (Biscoe) | 4 | Prairie County | 291 |
| Ulm | 5 | Prairie County | 179 |
Prairie County is the county generally considered as East Arkansas.