22 cities
| City | Rank | County | 2025 Pop. ↓ |
|---|---|---|---|
| Bishop | 1 | Inyo County | 3,726 |
| Dixon Lane-MeadowCreek | 2 | Inyo County | 3,012 |
| West Bishop | 3 | Inyo County | 2,711 |
| Sandy Valley | 4 | Inyo County | 1,706 |
| Big Pine | 5 | Inyo County | 1,419 |
| Lone Pine | 6 | Inyo County | 1,271 |
| Independence | 7 | Inyo County | 907 |
| Wilkerson | 8 | Inyo County | 603 |
| Chalfant | 9 | Inyo County | 590 |
| Round Valley | 10 | Inyo County | 537 |
| Swall Meadows | 11 | Inyo County | 466 |
| Mesa | 12 | Inyo County | 374 |
| Homewood Canyon | 13 | Inyo County | 225 |
| Goodsprings | 14 | Inyo County | 214 |
| Tecopa | 15 | Inyo County | 172 |
| Olancha | 16 | Inyo County | 130 |
| Furnace Creek | 17 | Inyo County | 118 |
| Kennedy Meadows | 18 | Inyo County | 107 |
| Cartago | 19 | Inyo County | 87 |
| Darwin | 20 | Inyo County | 85 |
| Keeler | 21 | Inyo County | 24 |
| Shoshone | 22 | Inyo County | 21 |
Inyo County is the county generally considered as East California.