22 cities
| City | Rank | County | 2025 Pop. ↓ |
|---|---|---|---|
| Bishop | 1 | Inyo County | 3,688 |
| Dixon Lane-MeadowCreek | 2 | Inyo County | 3,142 |
| West Bishop | 3 | Inyo County | 2,386 |
| Sandy Valley | 4 | Inyo County | 1,880 |
| Big Pine | 5 | Inyo County | 1,515 |
| Lone Pine | 6 | Inyo County | 1,145 |
| Independence | 7 | Inyo County | 895 |
| Round Valley | 8 | Inyo County | 815 |
| Wilkerson | 9 | Inyo County | 597 |
| Chalfant | 10 | Inyo County | 593 |
| Mesa | 11 | Inyo County | 405 |
| Swall Meadows | 12 | Inyo County | 401 |
| Homewood Canyon | 13 | Inyo County | 280 |
| Tecopa | 14 | Inyo County | 196 |
| Olancha | 15 | Inyo County | 166 |
| Furnace Creek | 16 | Inyo County | 163 |
| Kennedy Meadows | 17 | Inyo County | 116 |
| Darwin | 18 | Inyo County | 108 |
| Goodsprings | 19 | Inyo County | 97 |
| Cartago | 20 | Inyo County | 85 |
| Keeler | 21 | Inyo County | 35 |
| Shoshone | 22 | Inyo County | 29 |
Inyo County is the county generally considered as East California.