26 cities
| City | Rank | County | 2025 Pop. ↓ |
|---|---|---|---|
| Richmond | 1 | Madison County | 38,854 |
| Nicholasville | 2 | Jessamine County | 33,283 |
| Danville | 3 | Boyle County | 17,426 |
| Berea | 4 | Madison County | 16,260 |
| Campbellsville | 5 | Taylor County | 11,793 |
| Harrodsburg | 6 | Mercer County | 9,319 |
| Lebanon | 7 | Marion County | 6,669 |
| Wilmore | 8 | Jessamine County | 6,169 |
| Lancaster | 9 | Garrard County | 4,150 |
| Stanford | 10 | Lincoln County | 3,728 |
| Stanton | 11 | Powell County | 3,145 |
| Junction City | 12 | Boyle County | 2,299 |
| Irvine | 13 | Estill County | 2,237 |
| Clay City | 14 | Powell County | 1,169 |
| Burgin | 15 | Mercer County | 1,011 |
| McKee | 16 | Estill County | 803 |
| Perryville | 17 | Boyle County | 793 |
| Crab Orchard | 18 | Lincoln County | 765 |
| Loretto | 19 | Marion County | 712 |
| Ravenna | 20 | Estill County | 542 |
| Hustonville | 21 | Lincoln County | 405 |
| Bradfordsville | 22 | Marion County | 275 |
| Salvisa | 23 | Mercer County | 218 |
| Raywick | 24 | Marion County | 155 |
| St. Mary | 25 | Marion County | 146 |
| Keene | 26 | Jessamine County | 106 |
Madison County, Jessamine County, Boyle County, Taylor County, Lincoln County, Mercer County, Marion County, Garrard County, Estill County, and Powell County are the counties generally considered part of Central Kentucky.