29 cities
| City | Rank | County | 2025 Pop. ↓ |
|---|---|---|---|
| Bend | 1 | Deschutes County | 108,735 |
| Redmond | 2 | Deschutes County | 38,589 |
| Prineville | 3 | Crook County | 12,173 |
| Madras | 4 | Jefferson County | 7,833 |
| Deschutes River Woods | 5 | Deschutes County | 5,725 |
| Crooked River Ranch | 6 | Crook County | 5,580 |
| Three Rivers | 7 | Deschutes County | 3,949 |
| Juniper Canyon | 8 | Crook County | 3,561 |
| Eagle Crest | 9 | Crook County | 3,419 |
| Sisters | 10 | Deschutes County | 2,928 |
| La Pine | 11 | Deschutes County | 2,578 |
| Lakeview | 12 | Lake County | 2,416 |
| Warm Springs | 13 | Jefferson County | 2,330 |
| Culver | 14 | Jefferson County | 1,686 |
| Prineville Lake Acres | 15 | Crook County | 1,582 |
| Sunriver | 16 | Deschutes County | 1,547 |
| Terrebonne | 17 | Jefferson County | 1,308 |
| Metolius | 18 | Jefferson County | 1,039 |
| Tetherow | 19 | Deschutes County | 895 |
| Tumalo | 20 | Deschutes County | 737 |
| Seventh Mountain | 21 | Deschutes County | 592 |
| Camp Sherman | 22 | Jefferson County | 333 |
| Ochoco West | 23 | Crook County | 292 |
| Silver Lake | 24 | Lake County | 279 |
| New Pine Creek | 25 | Lake County | 272 |
| Paisley | 26 | Lake County | 247 |
| Pronghorn | 27 | Crook County | 229 |
| Plush | 28 | Lake County | 84 |
| Black Butte Ranch | 29 | Deschutes County | 66 |
Deschutes County, Crook County, Jefferson County, and Lake County are the counties generally considered part of Central Oregon.