US cities with populations over 1,000 starting with SANTA.
30 cities
| Rank | City | State | 2025 Pop. ↓ |
|---|---|---|---|
| 1 | Santa Ana | California | 310,069 |
| 2 | Santa Clarita | California | 218,442 |
| 3 | Santa Rosa | California | 174,435 |
| 4 | Santa Clara | California | 132,711 |
| 5 | Santa Maria | California | 110,123 |
| 6 | Santa Fe | New Mexico | 90,125 |
| 7 | Santa Monica | California | 87,928 |
| 8 | Santa Barbara | California | 84,990 |
| 9 | Santa Cruz | California | 60,541 |
| 10 | Santa Paula | California | 32,471 |
| 11 | Santa Fe Springs | California | 20,860 |
| 12 | Santaquin | Utah | 19,952 |
| 13 | Santa Clara | Oregon | 14,221 |
| 14 | Santa Fe | Texas | 13,127 |
| 15 | Santa Clara | Utah | 9,090 |
| 16 | Santa Teresa | New Mexico | 6,931 |
| 17 | Santa Ynez | California | 4,790 |
| 18 | Santa Rita Ranch | Texas | 4,569 |
| 19 | Santa Venetia | California | 3,658 |
| 20 | Santa Rosa | New Mexico | 2,715 |
| 21 | Santa Claus | Indiana | 2,620 |
| 22 | Santa Rosa | Texas | 2,314 |
| 23 | Santa Rosa Valley | California | 2,301 |
| 24 | Santa Anna township | Illinois | 2,272 |
| 25 | Santa Nella | California | 2,224 |
| 26 | Santa Clara | New Mexico | 1,588 |
| 27 | Santa Fe township | Illinois | 1,197 |
| 28 | Santa Susana | California | 1,156 |
| 29 | Santa Ana Pueblo | New Mexico | 1,105 |
| 30 | Santa Anna | Texas | 1,041 |
There are 30 cities in the United States that start with SANTA and have a population over 1,000.
The largest US city that starts with SANTA is Santa Ana, California with a population of 310,069.