16 cities
| City | Rank | County | 2026 Pop. ↓ |
|---|---|---|---|
| Parkersburg | 1 | Wood County | 28,414 |
| Vienna | 2 | Wood County | 10,290 |
| Williamstown | 3 | Wood County | 2,930 |
| St. Marys | 4 | Pleasants County | 1,706 |
| Harrisville | 5 | Ritchie County | 1,509 |
| Sistersville | 6 | Tyler County | 1,263 |
| Pennsboro | 7 | Ritchie County | 987 |
| Belmont | 8 | Pleasants County | 801 |
| North Hills | 9 | Wood County | 801 |
| Elizabeth | 10 | Wirt County | 662 |
| Middlebourne | 11 | Tyler County | 649 |
| Ellenboro | 12 | Ritchie County | 260 |
| Cairo | 13 | Ritchie County | 165 |
| Pullman | 14 | Ritchie County | 132 |
| Friendly | 15 | Tyler County | 91 |
| Auburn | 16 | Ritchie County | 74 |
Wood County, Ritchie County, Tyler County, Pleasants County, and Wirt County are the counties generally considered part of Northwest West Virginia.