There are 26 cities in Pickens County, South Carolina.
Note: As defined by the US Census Bureau, a city's official boundaries often extend miles beyond the city itself and may even cross county lines. As such, several thousand US cities officially exist in two or more counties (and therefore appear on multiple counties' lists of cities.)
City | Rank | State | 2024 Population | 2020 Census | Annual Change | Density (mi²) | Area (mi²) |
|---|---|---|---|---|---|---|---|
| Greenville | 1 | South Carolina | 73,394 | 71,114 | 0.78% | 2,440 | 30.08 |
| Easley | 2 | South Carolina | 27,503 | 23,035 | 4.23% | 2,091 | 13.15 |
| Clemson | 3 | South Carolina | 17,866 | 17,753 | 0.16% | 2,258 | 7.91 |
| Berea | 4 | South Carolina | 16,768 | 15,104 | 1.77% | 2,178 | 7.70 |
| Parker | 5 | South Carolina | 12,757 | 12,175 | 1.16% | 1,866 | 6.84 |
| Powdersville | 6 | South Carolina | 11,920 | 9,436 | 5.5% | 866 | 13.76 |
| Seneca | 7 | South Carolina | 9,105 | 8,856 | 0.69% | 1,105 | 8.24 |
| Clemson University | 8 | South Carolina | 7,105 | 5,329 | 6.67% | 3,356 | 2.12 |
| Welcome | 9 | South Carolina | 6,563 | 7,743 | -4.3% | 1,423 | 4.61 |
| Central | 10 | South Carolina | 5,340 | 5,268 | 0.34% | 1,643 | 3.25 |
| Pendleton | 11 | South Carolina | 3,709 | 3,499 | 1.42% | 756 | 4.91 |
| Dunean | 12 | South Carolina | 3,697 | 3,099 | 3.79% | 2,358 | 1.57 |
| Pickens | 13 | South Carolina | 3,388 | 3,400 | -0.09% | 1,108 | 3.06 |
| Liberty | 14 | South Carolina | 3,289 | 3,367 | -0.6% | 678 | 4.85 |
| Judson | 15 | South Carolina | 2,346 | 1,412 | 11.08% | 2,985 | 0.79 |
| Slater-Marietta | 16 | South Carolina | 2,300 | 2,098 | 2.27% | 534 | 4.31 |
| City View | 17 | South Carolina | 1,785 | 1,607 | 2.59% | 4,601 | 0.39 |
| Utica | 18 | South Carolina | 1,547 | 1,761 | -3.31% | 1,367 | 1.13 |
| Arial | 19 | South Carolina | 1,342 | 2,158 | -13.2% | 294 | 4.56 |
| Cateechee | 20 | South Carolina | 1,208 | 738 | 10.83% | 2,364 | 0.51 |
| La France | 21 | South Carolina | 1,126 | 856 | 6.43% | 869 | 1.30 |
| Sandy Springs | 22 | South Carolina | 772 | 974 | -6.08% | 269 | 2.87 |
| Six Mile | 23 | South Carolina | 752 | 758 | -0.27% | 369 | 2.04 |
| Norris | 24 | South Carolina | 747 | 747 | 0% | 396 | 1.88 |
| Dacusville | 25 | South Carolina | 178 | 307 | -10.1% | 81 | 2.19 |
| Caesars Head | 26 | South Carolina | 48 | 53 | 6.67% | 33 | 1.47 |
Note: City markers shown outside the county boundary mean that a part of the city extends into this county, but is primarily located in an adjacent county.
Greenville is the largest city in Pickens County.
Caesars Head is the smallest city in Pickens County.
There are 26 cities in Pickens County, South Carolina.