| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Craig | 1 | 1,065 | 1,037 | 0.28% | 159 | 7 | City |
| Klawock | 2 | 719 | 718 | -0.14% | 1,056 | 1 | City |
| Kake | 3 | 543 | 542 | -0.18% | 71 | 8 | City |
| Thorne Bay | 4 | 476 | 475 | -0.21% | 18 | 27 | City |
| Hydaburg | 5 | 377 | 379 | -0.26% | 1,291 | 0 | City |
| Coffman Cove | 6 | 126 | 127 | -0.79% | 12 | 11 | City |
| Whale Pass | 7 | 87 | 88 | -1.14% | 4.0 | 20 | City |
| Port Alexander | 8 | 74 | 74 | 0% | 19 | 4 | City |
| Kasaan | 9 | 29 | 29 | 0% | 5.0 | 6 | City |
| Edna Bay | 10 | 26 | 26 | 0% | 1.0 | 21 | City |
Craig is the largest city in Prince of Wales-Hyder Census Area, with a population of 1,065.
Edna Bay is the smallest city in Prince of Wales-Hyder Census Area, with a population of 26.
There are 10 cities in Prince of Wales-Hyder Census Area, Alaska.