City | 2024 Population |
|---|---|
| Easley | 27,503 |
| East Camden | 3,259 |
| East Gaffney | 2,901 |
| East Sumter | 505 |
| Eastover | 622 |
| Edgefield | 4,098 |
| Edisto | 1,815 |
| Edisto Beach | 1,055 |
| Edmund | 1,368 |
| Ehrhardt | 438 |
| Elgin | 1,649 |
| Elko | 141 |
| Elliott | 508 |
| Elloree | 544 |
| Enoree | 387 |
| Estill | 1,751 |
| Eureka Mill | 1,657 |
| Eutawville | 234 |