| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Lusk | 1 | 1,391 | 1,527 | -2.11% | 673 | 2 | Town |
| Manville | 2 | 90 | 92 | -1.1% | 331 | 0 | Town |
| Van Tassell | 3 | 23 | 24 | -4.17% | 13 | 2 | Town |
Lusk is the largest city in Niobrara County, with a population of 1,391.
Van Tassell is the smallest city in Niobrara County, with a population of 23.
There are 3 cities in Niobrara County, Wyoming.