11 cities
| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Greensboro | 1 | 313,135 | 295,873 | 0.93% | 2,324 | 135 | City |
| High Point | 2 | 120,518 | 114,767 | 0.8% | 2,096 | 57 | City |
| Archdale | 3 | 12,267 | 11,906 | 0.49% | 1,388 | 9 | City |
| Summerfield | 4 | 11,521 | 10,956 | 0.82% | 436 | 26 | Town |
| Gibsonville | 5 | 10,043 | 9,145 | 1.52% | 2,300 | 4 | Town |
| Oak Ridge | 6 | 8,029 | 7,641 | 0.82% | 479 | 17 | Town |
| Stokesdale | 7 | 6,208 | 5,917 | 0.8% | 326 | 19 | Town |
| Pleasant Garden | 8 | 5,228 | 4,997 | 0.75% | 348 | 15 | Town |
| Jamestown | 9 | 3,825 | 3,668 | 0.68% | 1,276 | 3 | Town |
| Sedalia | 10 | 705 | 675 | 0.71% | 353 | 2 | Town |
| Whitsett | 11 | 612 | 588 | 0.66% | 237 | 3 | Town |
Greensboro is the largest city in Guilford County, with a population of 313,135.
Whitsett is the smallest city in Guilford County, with a population of 612.
There are 11 cities in Guilford County, North Carolina.