| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Medford | 1 | 86,483 | 86,345 | -0.01% | 3,014 | 29 | City |
| Ashland | 2 | 20,784 | 21,379 | -0.5% | 3,132 | 7 | City |
| Central Point | 3 | 19,148 | 19,087 | 0.05% | 4,788 | 4 | City |
| Eagle Point | 4 | 9,885 | 9,717 | 0.24% | 3,331 | 3 | City |
| Talent | 5 | 6,293 | 6,316 | -0.05% | 4,732 | 1 | City |
| Phoenix | 6 | 4,936 | 4,530 | 0.33% | 2,586 | 2 | City |
| Shady Cove | 7 | 3,027 | 3,087 | -0.39% | 1,555 | 2 | City |
| Jacksonville | 8 | 2,952 | 3,049 | -0.67% | 1,560 | 2 | City |
| Rogue River | 9 | 2,273 | 2,387 | -0.87% | 2,355 | 1 | City |
| Gold Hill | 10 | 1,311 | 1,340 | -0.46% | 1,720 | 1 | City |
| Butte Falls | 11 | 430 | 443 | -0.69% | 1,005 | 0 | Town |
Medford is the largest city in Jackson County, with a population of 86,483.
Butte Falls is the smallest city in Jackson County, with a population of 430.
There are 11 cities in Jackson County, Oregon.