11 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Lovell | 1 | 2,423 | 2,240 | 1.55% | 2,199 | 1.10 | Town |
| Greybull | 2 | 1,753 | 1,643 | 1.27% | 792 | 2.21 | Town |
| Basin | 3 | 1,359 | 1,286 | 1.12% | 575 | 2.36 | Town |
| Powder Horn | 4 | 1,263 | 953 | 7.22% | 659 | 1.92 | CDP |
| Cowley | 5 | 899 | 764 | 3.1% | 1,030 | 0.87 | Town |
| Byron | 6 | 585 | 557 | 1.04% | 646 | 0.91 | Town |
| Burlington | 7 | 406 | 316 | 4.64% | 402 | 1.01 | Town |
| Garland | 8 | 206 | 193 | 3% | 61 | 3.39 | CDP |
| Deaver | 9 | 179 | 154 | 2.87% | 177 | 1.01 | Town |
| Manderson | 10 | 92 | 89 | 1.1% | 108 | 0.85 | Town |
| Hyattville | 11 | 58 | 100 | 7.41% | 14 | 4.10 | CDP |
Lovell is the largest city in Big Horn County, with a population of 2,423.
Hyattville is the smallest city in Big Horn County, with a population of 58.
There are 11 cities in Big Horn County, Wyoming.