4 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Lusk | 1 | 1,389 | 1,529 | -1.98% | 672 | 2 | Town |
| Manville | 2 | 91 | 93 | 0% | 335 | 0 | Town |
| Lance Creek | 3 | 61 | 27 | 7.02% | 1 | 42 | CDP |
| Van Tassell | 4 | 21 | 23 | 0% | 11 | 2 | Town |
Lusk is the largest city in Niobrara County, with a population of 1,389.
Van Tassell is the smallest city in Niobrara County, with a population of 21.
There are 4 cities in Niobrara County, Wyoming.