| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| La Crescent | 1 | 5,250 | 5,341 | -0.21% | 1,561 | 3 | City |
| Caledonia | 2 | 2,750 | 2,867 | -0.65% | 974 | 3 | City |
| Spring Grove | 3 | 1,195 | 1,260 | -0.91% | 1,202 | 1 | City |
| Houston | 4 | 964 | 1,000 | -0.62% | 783 | 1 | City |
| Brownsville | 5 | 540 | 567 | -0.92% | 292 | 2 | City |
| Hokah | 6 | 532 | 557 | -0.75% | 761 | 1 | City |
| Eitzen | 7 | 262 | 271 | -0.76% | 430 | 1 | City |
La Crescent is the largest city in Houston County, with a population of 5,250.
Eitzen is the smallest city in Houston County, with a population of 262.
There are 7 cities in Houston County, Minnesota.