| City | 2025 Pop. ↓ |
|---|---|
| Aiken | 32,828 |
| Anderson | 31,306 |
| Abbeville | 4,873 |
| Andrews | 2,515 |
| Allendale | 2,449 |
| Awendaw | 1,487 |
| Aynor | 1,082 |
| Arcadia Lakes | 853 |
| Atlantic Beach | 472 |
| City | 2025 Pop. ↓ |
|---|---|
| Bluffton | 38,101 |
| Beaufort | 14,511 |
| Bennettsville | 7,496 |
| Blythewood | 7,201 |
| Batesburg-Leesville | 5,334 |
| Belton | 4,630 |
| Barnwell | 4,573 |
| Burnettown | 3,269 |
| Bamberg | 2,914 |
| Bishopville | 2,851 |
| Blacksburg | 1,970 |
| Blackville | 1,901 |
| Branchville | 964 |
| Bowman | 763 |
| Briarcliffe Acres | 589 |
| Bonneau | 434 |
| Brunson | 412 |
| Bethune | 343 |
| Blenheim | 105 |
| City | 2025 Pop. ↓ |
|---|---|
| Charleston | 159,315 |
| Columbia | 146,933 |
| Conway | 30,776 |
| Clemson | 18,823 |
| Cayce | 13,617 |
| Camden | 9,172 |
| Clinton | 7,908 |
| Clover | 7,752 |
| Central | 5,356 |
| Chester | 5,219 |
| Cheraw | 4,932 |
| Cowpens | 2,279 |
| Chapin | 1,963 |
| Calhoun Falls | 1,752 |
| Chesterfield | 1,355 |
| Chesnee | 960 |
| Campobello | 786 |
| Cottageville | 724 |
| Coward | 716 |
| Clio | 566 |
| Cross Hill | 437 |
| Cameron | 373 |
| Carlisle | 314 |
| Central Pacolet | 242 |
| Cordova | 129 |
| Cope | 31 |
| City | 2025 Pop. ↓ |
|---|---|
| Easley | 27,992 |
| Edgefield | 4,206 |
| Estill | 1,759 |
| Elgin | 1,663 |
| Edisto Beach | 1,068 |
| Eastover | 631 |
| Elloree | 543 |
| Ehrhardt | 432 |
| Eutawville | 241 |
| Elko | 140 |
| City | 2025 Pop. ↓ |
|---|---|
| Florence | 41,129 |
| Fort Mill | 39,004 |
| Fountain Inn | 14,604 |
| Forest Acres | 10,392 |
| Folly Beach | 2,086 |
| Fairfax | 1,364 |
| Fort Lawn | 984 |
| Furman | 222 |
| City | 2025 Pop. ↓ |
|---|---|
| Greenville | 75,106 |
| Goose Creek | 51,375 |
| Greer | 48,937 |
| Greenwood | 22,694 |
| Gaffney | 12,498 |
| Georgetown | 8,931 |
| Great Falls | 1,920 |
| Gaston | 1,649 |
| Gray Court | 808 |
| Gilbert | 628 |
| Greeleyville | 354 |
| Gifford | 258 |
| Govan | 52 |
| City | 2025 Pop. ↓ |
|---|---|
| Hilton Head Island | 38,301 |
| Hanahan | 22,333 |
| Hardeeville | 15,394 |
| Hartsville | 7,340 |
| Hollywood | 5,555 |
| Honea Path | 3,933 |
| Hampton | 2,577 |
| Holly Hill | 1,250 |
| Heath Springs | 878 |
| Harleyville | 757 |
| Hickory Grove | 472 |
| Hemingway | 457 |
| Hilda | 421 |
| Hodges | 165 |
| City | 2025 Pop. ↓ |
|---|---|
| Irmo | 12,234 |
| Isle of Palms | 4,384 |
| Inman | 3,442 |
| Iva | 1,206 |
| City | 2025 Pop. ↓ |
|---|---|
| James Island | 12,558 |
| Johnston | 2,267 |
| Jackson | 1,662 |
| Johnsonville | 1,348 |
| Jonesville | 806 |
| Jefferson | 792 |
| Jamestown | 73 |
| Jenkinsville | 38 |
| City | 2025 Pop. ↓ |
|---|---|
| Kingstree | 3,011 |
| Kershaw | 2,080 |
| Kiawah Island | 2,000 |
| Kline | 141 |
| City | 2025 Pop. ↓ |
|---|---|
| Mount Pleasant | 96,692 |
| Myrtle Beach | 41,675 |
| Mauldin | 30,986 |
| Moncks Corner | 19,588 |
| Marion | 5,993 |
| Manning | 3,813 |
| Mullins | 3,805 |
| McColl | 1,953 |
| McCormick | 1,894 |
| Meggett | 1,467 |
| McBee | 818 |
| McClellanville | 631 |
| Mayesville | 549 |
| McConnells | 288 |
| Monetta | 209 |
| Mount Croghan | 135 |
| City | 2025 Pop. ↓ |
|---|---|
| North Charleston | 128,603 |
| North Augusta | 26,872 |
| North Myrtle Beach | 21,266 |
| Newberry | 10,918 |
| New Ellenton | 2,388 |
| Ninety Six | 2,075 |
| Norris | 755 |
| North | 673 |
| Neeses | 314 |
| Norway | 273 |
| Nichols | 218 |
| City | 2025 Pop. ↓ |
|---|---|
| Orangeburg | 13,428 |
| Olanta | 549 |
| Olar | 204 |
| City | 2025 Pop. ↓ |
|---|---|
| Port Royal | 16,988 |
| Pendleton | 3,747 |
| Pickens | 3,197 |
| Pacolet | 2,635 |
| Pageland | 2,535 |
| Pine Ridge | 2,362 |
| Pelzer | 1,449 |
| Prosperity | 1,258 |
| Pamplico | 1,061 |
| Pelion | 621 |
| Pinewood | 500 |
| Patrick | 288 |
| Paxville | 224 |
| Perry | 212 |
| Pawleys Island | 134 |
| Pomaria | 133 |
| Parksville | 132 |
| Plum Branch | 82 |
| Peak | 54 |
| City | 2025 Pop. ↓ |
|---|---|
| Quinby | 893 |
| City | 2025 Pop. ↓ |
|---|---|
| Rock Hill | 76,084 |
| Ridgeland | 3,741 |
| Ravenel | 2,722 |
| Reidville | 1,892 |
| Ridgeville | 1,084 |
| Ridge Spring | 591 |
| Ruby | 324 |
| Richburg | 268 |
| Ridgeway | 252 |
| Rowesville | 251 |
| Reevesville | 195 |
| Rockville | 142 |
| City | 2025 Pop. ↓ |
|---|---|
| Summerville | 53,042 |
| Sumter | 42,836 |
| Spartanburg | 39,856 |
| Simpsonville | 29,196 |
| Seneca | 9,287 |
| Surfside Beach | 4,420 |
| Saluda | 3,056 |
| Springdale | 2,760 |
| South Congaree | 2,394 |
| Seabrook Island | 2,155 |
| Sullivan's Island | 1,961 |
| St. George | 1,859 |
| St. Matthews | 1,830 |
| St. Stephen | 1,597 |
| Santee | 810 |
| Swansea | 782 |
| Summerton | 774 |
| Six Mile | 761 |
| Scranton | 656 |
| Sharon | 472 |
| Summit | 469 |
| Springfield | 434 |
| Society Hill | 424 |
| Salley | 355 |
| Snelling | 253 |
| Stuckey | 187 |
| Starr | 176 |
| Silverstreet | 170 |
| Scotia | 158 |
| Sellers | 146 |
| Sycamore | 140 |
| Salem | 129 |
| Smoaks | 97 |
| Smyrna | 55 |
| City | 2025 Pop. ↓ |
|---|---|
| Tega Cay | 14,647 |
| Travelers Rest | 9,245 |
| Timmonsville | 2,121 |
| Turbeville | 738 |
| Trenton | 462 |
| Troy | 87 |
| Tatum | 69 |
| City | 2025 Pop. ↓ |
|---|---|
| West Columbia | 18,643 |
| Walterboro | 5,484 |
| Woodruff | 5,280 |
| Williamston | 4,342 |
| Walhalla | 4,291 |
| Wellford | 3,832 |
| Winnsboro | 3,250 |
| Williston | 2,875 |
| Westminster | 2,460 |
| Ware Shoals | 1,719 |
| Whitmire | 1,450 |
| West Pelzer | 1,041 |
| Wagener | 702 |
| West Union | 392 |
| Waterloo | 157 |
| Woodford | 155 |
| Ward | 124 |
| Windsor | 124 |
| Williams | 97 |