14 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Manitowoc | 1 | 34,524 | 34,633 | -0.06% | 1,923 | 17.95 | City |
| Two Rivers | 2 | 11,105 | 11,264 | -0.29% | 1,834 | 6.06 | City |
| Kiel | 3 | 3,962 | 3,946 | 0.08% | 1,567 | 2.53 | City |
| Cleveland | 4 | 1,568 | 1,582 | -0.19% | 794 | 1.98 | Village |
| Mishicot | 5 | 1,418 | 1,430 | -0.14% | 556 | 2.55 | Village |
| Reedsville | 6 | 1,196 | 1,196 | 0% | 987 | 1.21 | Village |
| Valders | 7 | 970 | 955 | 0.31% | 674 | 1.44 | Village |
| Whitelaw | 8 | 732 | 741 | -0.27% | 1,394 | 0.53 | Village |
| St. Nazianz | 9 | 720 | 714 | 0.14% | 907 | 0.79 | Village |
| Francis Creek | 10 | 668 | 657 | 0.3% | 588 | 1.14 | Village |
| Maribel | 11 | 328 | 335 | -0.3% | 287 | 1.14 | Village |
| Kellnersville | 12 | 303 | 310 | -0.33% | 562 | 0.54 | Village |
| Collins | 13 | 230 | 209 | 1.77% | 135 | 1.71 | CDP |
| Clarks Mills | 14 | 163 | 139 | 7.24% | 657 | 0.25 | CDP |
Manitowoc is the largest city in Manitowoc County, with a population of 34,524.
Clarks Mills is the smallest city in Manitowoc County.
There are 14 cities in Manitowoc County, Wisconsin.