46 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Frederick | 1 | 92,322 | 78,134 | 3.11% | 3,853 | 24 | City |
| Frederick | 2 | 92,322 | 78,395 | 3.11% | 3,853 | 24 | City |
| Ballenger Creek | 3 | 25,838 | 21,484 | 1.99% | 2,393 | 11 | CDP |
| Green Valley | 4 | 16,225 | 12,391 | 7.15% | 949 | 17 | CDP |
| Urbana | 5 | 14,423 | 12,362 | 2.49% | 1,856 | 8 | CDP |
| Linganore | 6 | 12,702 | 9,988 | 2.24% | 1,535 | 8 | CDP |
| Mount Airy | 7 | 9,980 | 9,659 | 0.67% | 2,421 | 4 | Town |
| Mount Airy | 8 | 9,980 | 9,647 | 0.67% | 2,421 | 4 | Town |
| Brunswick | 9 | 9,319 | 7,770 | 3.37% | 2,845 | 3 | City |
| Brunswick | 10 | 9,319 | 7,799 | 3.37% | 2,845 | 3 | City |
| Walkersville | 11 | 6,626 | 6,156 | 1.39% | 1,391 | 5 | Town |
| Walkersville | 12 | 6,626 | 6,169 | 1.39% | 1,391 | 5 | Town |
| Thurmont | 13 | 6,335 | 6,214 | 0.43% | 2,039 | 3 | Town |
| Thurmont | 14 | 6,335 | 6,200 | 0.43% | 2,039 | 3 | Town |
| Spring Ridge | 15 | 5,665 | 5,612 | -0.16% | 2,104 | 3 | CDP |
| Middletown | 16 | 5,081 | 4,944 | 0.51% | 2,399 | 2 | Town |
| Middletown | 17 | 5,081 | 4,949 | 0.51% | 2,399 | 2 | Town |
| Monrovia | 18 | 3,621 | 1,556 | 6.28% | 1,613 | 2 | CDP |
| Emmitsburg | 19 | 2,958 | 2,772 | 1.3% | 1,829 | 2 | Town |
| Emmitsburg | 20 | 2,958 | 2,768 | 1.3% | 1,829 | 2 | Town |
| Braddock Heights | 21 | 2,919 | 3,093 | 0.72% | 547 | 5 | CDP |
| Jefferson | 22 | 2,900 | 2,577 | 1.86% | 1,041 | 3 | CDP |
| Bartonsville | 23 | 2,604 | 1,786 | 3.05% | 1,219 | 2 | CDP |
| Point Rocks | 24 | 2,584 | 2,067 | 2.99% | 2,307 | 1 | CDP |
| Adamstown | 25 | 2,400 | 2,130 | 0.08% | 2,256 | 1 | CDP |
| Myersville | 26 | 1,880 | 1,806 | 0.8% | 1,619 | 1 | Town |
| Myersville | 27 | 1,880 | 1,802 | 0.8% | 1,619 | 1 | Town |
| New Market | 28 | 1,629 | 1,526 | 1.24% | 920 | 2 | Town |
| New Market | 29 | 1,629 | 1,526 | 1.24% | 920 | 2 | Town |
| Libertytown | 30 | 1,356 | 831 | 2.03% | 563 | 2 | CDP |
| Buckeystown | 31 | 1,289 | 1,289 | 1.42% | 1,412 | 1 | CDP |
| Woodsboro | 32 | 1,119 | 1,093 | 0.45% | 1,583 | 1 | Town |
| Woodsboro | 33 | 1,119 | 1,091 | 0.45% | 1,583 | 1 | Town |
| Highfield-Cascade | 34 | 1,011 | 912 | -0.69% | 584 | 2 | CDP |
| Sabillasville | 35 | 418 | 390 | 0.97% | 250 | 2 | CDP |
| Lewistown | 36 | 409 | 410 | 7.07% | 639 | 1 | CDP |
| Garretts Mill | 37 | 334 | 350 | 2.14% | 585 | 1 | CDP |
| Rosemont | 38 | 270 | 266 | 0.37% | 486 | 1 | Village |
| Rosemont | 39 | 270 | 265 | 0.37% | 486 | 1 | Village |
| Graceham | 40 | 254 | 304 | 7.17% | 530 | 0 | CDP |
| Edgemont | 41 | 247 | 277 | 0.41% | 466 | 1 | CDP |
| Sandy Hook | 42 | 207 | 193 | 0.49% | 958 | 0 | CDP |
| Yarrowsburg | 43 | 182 | 274 | 2.25% | 802 | 0 | CDP |
| Burkittsville | 44 | 145 | 142 | 0% | 319 | 0 | Town |
| Burkittsville | 45 | 145 | 142 | 0% | 319 | 0 | Town |
| Greensburg | 46 | 89 | 126 | -9.18% | 220 | 0 | CDP |
Frederick is the largest city in Frederick County, with a population of 92,322.
Greensburg is the smallest city in Frederick County, with a population of 89.
There are 46 cities in Frederick County, Maryland.