6 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Hartsville-Trousdale County | 1 | 12,695 | 11,635 | 1.7% | 111 | 114.34 | Township |
| Lafayette | 2 | 6,002 | 5,594 | 1.39% | 1,133 | 5.30 | City |
| Red Boiling Springs | 3 | 1,220 | 1,205 | 0.25% | 697 | 1.75 | City |
| Fairfield | 4 | 300 | 200 | 4.17% | 303 | 0.99 | CDP |
| Oak Grove | 5 | 145 | 120 | -3.33% | 113 | 1.28 | CDP |
| Bransford | 6 | 121 | 269 | -2.42% | 30 | 4.03 | CDP |
Hartsville-Trousdale County is the largest city in Macon County, with a population of 12,695.
Bransford is the smallest city in Macon County.
There are 6 cities in Macon County, Tennessee.