3 cities
| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Hartsville-Trousdale County | 1 | 12,421 | 11,634 | 1.07% | 109 | 114 | Township |
| Lafayette | 2 | 6,085 | 5,587 | 1.38% | 1,149 | 5 | City |
| Red Boiling Springs | 3 | 1,217 | 1,208 | 0.16% | 695 | 2 | City |
Hartsville-Trousdale County is the largest city in Macon County, with a population of 12,421.
Red Boiling Springs is the smallest city in Macon County, with a population of 1,217.
There are 3 cities in Macon County, Tennessee.