| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| St. Francis | 1 | 1,264 | 1,270 | -0.08% | 1,475 | 1 | City |
| Bird City | 2 | 440 | 437 | 0.23% | 194 | 2 | City |
| McDonald | 3 | 114 | 117 | -0.87% | 521 | 0 | City |
St. Francis is the largest city in Cheyenne County, with a population of 1,264.
McDonald is the smallest city in Cheyenne County, with a population of 114.
There are 3 cities in Cheyenne County, Kansas.