| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Salina | 1 | 45,880 | 46,842 | -0.46% | 1,753 | 26 | City |
| Assaria | 2 | 419 | 430 | -0.48% | 1,791 | 0 | City |
| Gypsum | 3 | 384 | 404 | -0.78% | 1,027 | 0 | City |
| Brookville | 4 | 234 | 241 | -0.85% | 407 | 1 | City |
| New Cambria | 5 | 106 | 105 | 0% | 596 | 0 | City |
Salina is the largest city in Saline County, with a population of 45,880.
New Cambria is the smallest city in Saline County, with a population of 106.
There are 5 cities in Saline County, Kansas.