| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Spearfish | 1 | 14,541 | 12,239 | 2.73% | 842 | 17 | City |
| Lead | 2 | 3,075 | 2,978 | 0.36% | 1,494 | 2 | City |
| Deadwood | 3 | 1,407 | 1,149 | 3.46% | 285 | 5 | City |
| Whitewood | 4 | 996 | 897 | 1.53% | 1,564 | 1 | City |
| Central City | 5 | 114 | 101 | 1.79% | 770 | 0 | City |
Spearfish is the largest city in Lawrence County, with a population of 14,541.
Central City is the smallest city in Lawrence County, with a population of 114.
There are 5 cities in Lawrence County, South Dakota.