6 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Pierre | 1 | 13,762 | 14,057 | -0.43% | 1,056 | 13.03 | City |
| Oahe Acres | 2 | 494 | 536 | 7.16% | 374 | 1.32 | CDP |
| Blunt | 3 | 336 | 341 | -0.3% | 690 | 0.49 | City |
| Harrold | 4 | 98 | 102 | -1.01% | 238 | 0.41 | Town |
| Cow Creek | 5 | 93 | 90 | 8.14% | 51 | 1.84 | CDP |
| Raber township | 6 | 35 | 30 | 6.06% | 1 | 51.70 | Township |
Pierre is the largest city in Hughes County, with a population of 13,762.
Raber township is the smallest city in Hughes County.
There are 6 cities in Hughes County, South Dakota.