9 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Spearfish | 1 | 14,197 | 12,225 | 2.85% | 824 | 17 | City |
| Lead | 2 | 3,052 | 2,979 | 0.46% | 1,483 | 2 | City |
| Deadwood | 3 | 1,395 | 1,152 | 3.56% | 283 | 5 | City |
| Whitewood | 4 | 982 | 897 | 1.76% | 1,542 | 1 | City |
| Boulder Canyon | 5 | 706 | 411 | 7.13% | 231 | 3 | CDP |
| Blucksberg Mountain | 6 | 658 | 440 | 2.02% | 984 | 1 | CDP |
| St. Onge | 7 | 371 | 327 | 1.64% | 10 | 36 | Township |
| Central City | 8 | 110 | 99 | 1.85% | 743 | 0 | City |
| Whitewood | 9 | 94 | 91 | 0% | 2 | 49 | Township |
Spearfish is the largest city in Lawrence County, with a population of 14,197.
Whitewood is the smallest city in Lawrence County, with a population of 94.
There are 9 cities in Lawrence County, South Dakota.