9 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Wagner | 1 | 1,387 | 1,484 | -1.35% | 747 | 1.86 | City |
| Platte | 2 | 1,208 | 1,293 | -1.39% | 1,148 | 1.05 | City |
| Lake Andes | 3 | 667 | 712 | -1.33% | 894 | 0.75 | City |
| Pickstown | 4 | 230 | 225 | 0.44% | 375 | 0.61 | Town |
| Geddes | 5 | 148 | 158 | -1.33% | 204 | 0.73 | City |
| Marty | 6 | 146 | 265 | -10.43% | 45 | 3.22 | CDP |
| Ravinia | 7 | 69 | 69 | 0% | 277 | 0.25 | Town |
| Dante | 8 | 67 | 69 | 0% | 134 | 0.50 | Town |
| Clearfield Colony | 9 | 50 | 0 | 6.38% | 165 | 0.30 | CDP |
Wagner is the largest city in Charles Mix County, with a population of 1,387.
Clearfield Colony is the smallest city in Charles Mix County.
There are 9 cities in Charles Mix County, South Dakota.