4 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Leitchfield | 1 | 6,497 | 6,411 | 0.26% | 604 | 10.76 | City |
| Clarkson | 2 | 963 | 937 | 0.52% | 905 | 1.06 | City |
| Caneyville | 3 | 532 | 527 | 0.19% | 323 | 1.65 | City |
| Big Clifty | 4 | 284 | 294 | 7.17% | 197 | 1.44 | CDP |
Leitchfield is the largest city in Grayson County, with a population of 6,497.
Big Clifty is the smallest city in Grayson County.
There are 4 cities in Grayson County, Kentucky.